Eric C.B. Milner, PhD

Education

  • The University of Texas Southwestern Medical Center, Dallas, TX, Dept Microbiology, Postdoctoral Fellow (1980 - 1983)
  • Ph.D., Microbiology, University of Montana, Missoula, 1980
  • M.S., Microbiology, University of Montana, Missoula, 1976
  • A.B., Zoology, University of California (Berkeley), 1972


    • Professional Appointments

  • Editor, BioMedical Science Writers, LLC (2006 – Present)

  • Co-Director, Rochester Program for Biodefense of Immunocompromised Populations, University of Rochester Medical Center, Rochester, NY (2005 – 2007)

  • Div Rheumatology, Allergy, & Immunology, Dept Medicine, University of Rochester Medical Center, Rochester, NY; Associate Professor (2004 – 2007)

  • Vaccinex Corporation, Rochester, NY; Group Leader (2002 – 2004)

  • Virginia Mason Research Center, Seattle, WA (1986 – 2001)  Immunology Program, Assistant Member 1986; Associate Member 1992; Member 1999 

  • University of Washington School of Medicine, Seattle, WA (1987 – 2001) Pathology, Affiliate Assistant Professor 1987; Immunology, Affiliate Assistant Professor 1989; Affiliate Associate Professor 1994; Graduate Faculty 1994

  • The University of Texas Southwestern Medical Center, Dallas, TX  Dept Microbiology, Assistant Instructor (1984 - 1986)


    • Awards, Fellowships, & Grants)

  • NIH NIAID N01 (Co-Principal Investigator) 2005 – 2007
  • NIH NIAID N01 (Investigator) 2005 – 2007
  • NIH NIDCR R01 (Investigator) 2006 – 2007
  • NIST Advanced Technology award (Principal Investigator) 2004 – 2006
  • NIH NIAID R43 (Principal Investigator) 2004 – 2006
  • NIH NIAMS R01 (Principal Investigator) 1997 – 2001
  • NIH NIAMS R21 [High risk/High reward] (Principal Investigator) 1997 – 1999
  • National Arthritis Foundation Biomedical Science Grant (Principal Investigator) 1996 – 1999
  • NIH NIDDK P01 (Sub-Project Principal Investigator) 1995 – 2000
  • American Cancer Society Research Grant (Principal Investigator) 1994 – 1996
  • NIH NIAMS R01 (Principal Investigator) 1994 – 1997
  • American Cancer Society Research Grant (Principal Investigator) 1991 – 1994
  • NIH NIAID P01 (Sub-Project Principal Investigator) 1991 – 1995
  • NIH NIDDK P01 (Sub-Project Principal Investigator) 1990 – 1995
  • March of Dimes Predoctoral Fellowship (Sponsor) 1989 – 1992
  • American Cancer Society Research Grant (Principal Investigator) 1989 – 1991
  • NIH NIAMS R29 (Principal Investigator) 1989 – 1994
  • National Arthritis Foundation Biomedical Science Grant (Principal Investigator) 1989 – 1992
  • American Cancer Society Research Grant (Principal Investigator) 1987 – 1989
  • National Arthritis Foundation Investigator Award (Principal Investigator) 1984 – 1987
  • National Arthritis Foundation Postdoctoral Fellowship (Fellow) 1981 – 1984
  • NIH Training Grant, Department of Cell Biology, The University of Texas Health Science Center at Dallas. (Fellow) 1980 – 1981
  • Predoctoral Student, Laboratory of Microbial Structure and Function, Rocky Mountain Laboratories, NIAID, NIH, Hamilton, MT 1978 – 1980
  • Teaching Assistant, Dept Microbiology, Univ MT, Missoula, MT 1973 - 1978
  • National Merit Scholarship Commendation 1967


    • Societies

  • The Henry Kunkel Society
  • New York Academy of Sciences
  • American Association of Immunologists


    • Service

  • 2011 - 2014 IACUC NIH NIAID Rocky Mountain Laboratories
  • 2000 NIH Special Emphasis Panel ZRG1 IMS (3)
  • 1999 The Wellcome Trust Ad Hoc reviewer
  • 1997 NSF Ad Hoc reviewer
  • 1997 USDA NRI Ad Hoc reviewer
  • 1996 - 1998 Arthritis Foundation Molecular Immunology Study Section
  • 1996 Ad Hoc reviewer for U Washington Royalty Research Fund
  • 1995 NCI Ad Hoc study section
  • 1991 - 1992 Arthritis Foundation Molecular Biology Study Section
  • 1990 Arthritis Foundation Biomedical Grants Subcommittee
  • 1989 - 1994 VMRC Management Committee


    • Editorial Board Service

  • Associate Editor, Journal of Immunology
  • Reviewer for: American Journal of Human Genetics, Analytical Biochemistry, Arthritis Research, Autoimmunity, Biotechniques, Blood, Cellular Immunology, Clinical and Experimental Immunology, Developmental Immunology, Diabetes, Experimental and Clinical Immunogenetics, Human Immunology, Human Molecular Genetics, Infection and Immunity, International Immunology, Journal of Immunology, Journal of Clinical Investigation, Molecular Immunology, Nucleic Acids Research, Proceedings of the National Academy of Sciences USA, Scandinavian Journal of Immunology


    • Patent

  • DNA probes to VNTR loci (No. 5,032,501)


    • Publications

    ARTICLES
  • Quách TD, Manjarrez-Orduño N, Adlowitz DG, Silver L, Yang H, Wei C, Milner ECB, Sanz I. 2011. Anergic Responses Characterize a Large Fraction of Human Autoreactive Naive B Cells Expressing Low Levels of Surface IgM. J Immunol. 186:4640-4648.
  • Anolik JH, Ravikumar R, Barnard J, Owen T, Almudevar A, Milner EC, Miller CH, Dutcher PO, Hadley JA, Sanz I. 2008. Cutting edge: anti-tumor necrosis factor therapy in rheumatoid arthritis inhibits memory B lymphocytes via effects on lymphoid germinal centers and follicular dendritic cell networks. J. Immunol. 180:688-692.
  • Wei,C., J.Anolik, A.Cappione, B.Zheng, A.Pugh-Bernard, J.Brooks, E.H.Lee, E.C.B.Milner, and I.Sanz. 2007. A New Population of Cells Lacking Expression of CD27 Represents a Notable Component of the B Cell Memory Compartment in Systemic Lupus Erythematosus. J. Immunol. 178:6624-6633.
  • Huggins J, Pellegrin T, Felgar RE, Wei C, Brown M, Zheng B, Milner ECB, Bernstein SH, Sanz I, Zand MS. 2006. CpG DNA activation and plasma cell differentiation of CD27- naive human B cells. Blood. 109:1611-1619.
  • Anolik JH, Friedberg JW, Zheng B, Barnard J, Owen T, Cushing E, Kelly J, Milner ECB, Fisher RI, Sanz I. 2007. B cell reconstitution after rituximab treatment of lymphoma recapitulates B cell ontogeny. Clin Immunol. 122:139-145.
  • Milner, E.C.B., J. Anolik, A. Cappione and I. Sanz. 2005. Human Innate B-cells: A Link Between Host Defense and Autoimmunity? Springer Seminars in Immunopathol. 26:433-452.
  • Glas,A.M., E.H.N.van Montfort, and E.C.B.Milner. 2000. The human antibody repertoire: old notions, current realities, and VH gene-dependent biases. In The antibodies, Volume 6. M.Zanetti and J.D.Capra, editors. Harwood Academic Publishers, Amsterdam. 63-79.
  • Glas,A.M., E.H.N.van Montfort, J.Storek, E.N.Green, R.P.Drissen, V.J.Bechtold, Z.J.Reilly, M.Dawson, and E.C.B.Milner. 2000. B cell-autonomous somatic mutation deficit following bone marrow transplant. Blood 96:1064-1069.
  • Scamurra,R.W., D.J.Miller, L.Dahl, M.Abrahamson, V.Kapur, S.M.Wahl, E.C.B.Milner, and E.N.Janoff. 2000. Impact of HIV-1 infection on VH3 gene repertoire of naive human B cells. J.Immunol. 164:5482-5491.
  • Glas,A.M., S.-C.Huang, E.H.N.van Montfort, and E.C.B.Milner. 1999. Motif-specific probes identify individual genes and detect somatic mutations. Mol.Immunol. 36:599-610.
  • Huang,S.-C., A.M.Glas, G.V.Pinchuk, E.H.N.van Montfort, S.P.Rao, R.Jiang, and E.C.B.Milner. 1999. Human B cells accumulate immunoglobulin V gene somatic mutations in a cell contact-dependent manner in cultures supported by activated T cells but not in cultures supported by CD40-ligand. Clin.Exp.Immunol. 116:441-448.
  • Huang,S.-C., R.Jiang, W.O.Hufnagle, D.E.Furst, K.R.Wilske, and E.C.B.Milner. 1998. VH usage and somatic hypermutation in peripheral blood B cells of patients with rheumatoid arthritis. Clin.Exp.Immunol. 112:516-527.
  • Glas,A.M., C.Nottenburg, and E.C.B.Milner. 1997. Analysis of rearranged immunoglobulin heavy chain variable region genes obtained from a bone marrow transplant (BMT) recipient. Clin.Exp.Immunol. 107:372-380.
  • Kraj,P., S.P.Rao, A.M.Glas, R.R.Hardy, E.C.B.Milner, and L.E.Silberstein. 1997. The human heavy chain Ig V region gene repertoire is biased at all stages of B cell ontogeny, including early pre-B cells. J.Immunol. 158:5824-5832.
  • Huang,S.-C., R.Jiang, A.M.Glas, and E.C.B.Milner. 1996. Nonstochastic utilization of Ig V region genes in unselected human peripheral B cells. Mol.Immunol. 33:553-560.
  • Milner,E.C.B. 1996. Organization of the human VH locus and rearrangement patterns of the V H3 gene family. In Human B-cell superantigens. M.Zouali, editor. R.G. Landes Company, Austin. 1-10.
  • Pinchuk,G.V., C.M.Alexander, A.M.Glas, R.J.Armitage, and E.C.B.Milner. 1996. VH4 repertoire in human B lymphocytes stimulated by CD40 ligand and IL-4: evidence for positive and negative selection mechanisms coupled to CD40 activation. Mol.Immunol. 33:1369-1376.
  • Rao,S.P., S.-C.Huang, and E.C.B.Milner. 1996. Analysis of the VH3 repertoire among genetically disparate individuals. Exp.Clin.Immunogenet. 13:131-138.
  • Suzuki,I., E.C.B.Milner, A.M.Glas, W.O.Hufnagle, S.P.Rao, L.Pfister, and C.Nottenburg. 1996. Immunoglobulin heavy chain variable region gene usage in bone marrow transplant recipients: lack of somatic mutation indicates a maturational arrest. Blood 87:1873-1880.
  • Glas,A.M., W.O.Hufnagle, I.Suzuki, L.Pfister, S.Rao, C.Nottenburg, and E.C.B.Milner. 1995. Anomalous diversification of the antibody repertoire following bone marrow transplantation. Ann.N.Y.Acad.Sci. 764:312-314.
  • Hufnagle,W.O., S.-C.Huang, I.Suzuki, and E.C.B.Milner. 1995. A complete preimmune human VH3 repertoire. Ann.N.Y.Acad.Sci. 764:293-295.
  • Milner,E.C.B., W.O.Hufnagle, A.M.Glas, I.Suzuki, and C.M.Alexander. 1995. Polymorphism and utilization of human VH genes. Ann.N.Y.Acad.Sci. 764:50-61.
  • Pinchuk,G.V., C.Nottenburg, and E.C.B.Milner. 1995. Patterns of V-region gene segment association in the human antibody response to Haemophilus influenzae type B capsular polysaccharide (Hib PS). Ann.N.Y.Acad.Sci. 764:378-380.
  • Pinchuk,G.V., C.Nottenburg, and E.C.B.Milner. 1995. Predominant V-region gene configurations in the human antibody response to Haemophilus influenzae capsular polysaccharide. Scand.J.Immunol. 41:324-330.
  • Suzuki,I., L.Pfister, A.Glas, C.Nottenburg, and E.C.B.Milner. 1995. Representation of rearranged VH gene segments in the human adult antibody repertoire. J.Immunol. 154:3902-3911.
  • Sasso,E.H., K.Willems van Dijk, A.Bull, and E.C.B.Milner. 1993. A fetally expressed VH1 gene belongs to a complex set of alleles. J.Clin.Invest. 91:2358-2367.
  • van der Maarel,S.M., K.Willems van Dijk, C.M.Alexander, E.H.Sasso, A.B.Bull, and E.C.B.Milner. 1993. Chromosomal organization of the human VH4 gene family: Location of individual gene segments. J.Immunol. 150:2858-2868.
  • Willems van Dijk,K., F.Mortari, P.M.Kirkham, H.W.Schroeder, Jr., and E.C.B.Milner. 1993. The human immunoglobulin VH7 gene family consists of a small, polymorphic group of six to eight gene segments dispersed throughout the VH locus. Eur.J.Immunol. 23:832-839.
  • Hillson,J.L., I.R.Oppliger, E.H.Sasso, E.C.B.Milner, and M.H.Wener. 1992. The emerging B cell repertoire: influence of developmental stage and interindividual variation. J.Immunol. 149:3741-3752.
  • Sasso,E.H., K.Willems van Dijk, A.Bull, S.M.van der Maarel, and E.C.B.Milner. 1992. VH genes in tandem array comprise a repeated germline motif. J.Immunol. 149:1230-1236.
  • Weiffenbach,B., R.G.Bagley, K.Falls, J.Dubois, C.Hyser, D.Storvick, P.Schultz, J.R.Mendell, E.C.B.Milner, S.J.Jacobsen, and R.C.Griggs. 1992. Framework multipoint map of the long arm of human chromosome 4 and telomeric localization of the gene for FSHD. Mam.Gen. 3:143-150.
  • Weiffenbach,B., R.G.Bagley, K.Falls, C.Hyser, D.Storvick, S.J.Jacobsen, P.Schultz, J.Mendell, K.Willems van Dijk, E.C.B.Milner, and R.Griggs. 1992. Linkage analysis of five chromosome 4 markers localizes the facioscapulohumeral muscular dystrophy (FSHD) gene to distal 4q35. Am.J.Hum.Genet. 51:416-423.
  • Willems van Dijk,K., L.A.Milner, and E.C.B.Milner. 1992. Mapping of human H chain V region genes (VH4) using deletional analysis and pulsed field gel electrophoresis. J.Immunol. 148:2923-2931.
  • Willems van Dijk,K., L.A.Milner, E.H.Sasso, and E.C.B.Milner. 1992. Chromosomal organization of the heavy chain variable region gene segments comprising the human fetal antibody repertoire. Proc.Natl.Acad.Sci.USA 89:10430-10434.
  • Milner,E.C.B., K.Willems van Dijk, and E.H.Sasso. 1991. The human VH locus. In Molecular Mechanisms of IMMUNE REGULATION. R.Srivastava, B.P.Ram, and P.Tyle, editors. VCH Publishers, New York. 135-158.
  • Wijmenga,C., G.W.Padberg, P.Moerer, J.Wiegant, L.Liem, O.F.Brouwer, E.C.B.Milner, J.L.Weber, G.B.van Ommen, L.A.Sandkuyl, and R.R.Frants. 1991. Mapping of facioscapulohumeral muscular dystrophy gene to chromosome 4q35-qter by multipoint linkage analysis and in situ hybridization. Genomics 9:570-575.
  • Willems van Dijk,K., E.H.Sasso, and E.C.B.Milner. 1991. Polymorphism of the human immunoglobulin VH4 gene family. J.Immunol. 146:3646-3651.
  • Hiraiwa,A., D.J.Nugent, and E.C.B.Milner. 1990. Sequence analysis of monoclonal antibodies derived from a patient with idiopathic thrombocytopenic purpura. Autoimmunity 8:107-113.
  • Kwok,W.W., E.Mickelson, S.Masewicz, E.C.B.Milner, J.Hansen, and G.T.Nepom. 1990. Polymorphic DQa and DQb interactions dictate HLA class II determinants of allo-recognition. J.Exp.Med. 171:85-95.
  • Sasso,E.H., K.Willems van Dijk, and E.C.B.Milner. 1990. Variation in prevalence of related human VH3 germline genes. ICSU Short Rep. 10:17-17.
  • Sasso,E.H., K.Willems van Dijk, and E.C.B.Milner. 1990. Prevalence and polymorphism of human VH3 genes. J.Immunol. 145:2751-2757.
  • Hiraiwa,A., C.E.Seyfried, G.T.Nepom, and E.C.B.Milner. 1989. Sequence analysis of HLA class II domains: Characterization of the DQw3 family of DQb genes. Immunogenetics 29:186-190.
  • Kwok,W., C.Lotshaw, E.C.B.Milner, N.Knitter-Jack, and G.T.Nepom. 1989. Mutational analysis of the HLA DQ3.2 insulin-dependent diabetes mellitus susceptibility gene. Proc.Natl.Acad.Sci.USA 86:1027-1030.
  • Milner,E.C.B., C.L.Lotshaw, K.Willems van Dijk, P.Charmley, P.Concannon, and H.W.Schroeder, Jr. 1989. Isolation and mapping of a polymorphic DNA sequence pH30 on chromosome 4 [HGM provisional no. D4S139]. Nucleic Acids Res. 17:4002-4002.
  • Willems van Dijk,K., H.W.Schroeder, Jr., R.M.Perlmutter, and E.C.B.Milner. 1989. Heterogeneity in the human immunoglobulin VH locus. J.Immunol. 142:2547-2554.
  • Hiraiwa,A. and E.C.B.Milner. 1988. Locus-specific vector/primer systems for rapid cloning of allelic variants. Gene 71:193-199.
  • Rathbun,G.A., F.Otani, E.C.B.Milner, J.D.Capra, and P.W.Tucker. 1988. Molecular characterization of the A/J J558 family of heavy chain variable region gene segments. J.Mol.Biol. 202:383-395.
  • Schroeder,H.W., Jr., M.A.Walter, M.H.Hofker, A.Ebens, K.Willems van Dijk, L.C.Liao, D.Cox, E.C.B.Milner, and R.M.Perlmutter. 1988. Physical linkage of a human immunoglobulin heavy chain variable region gene segment to diversity and joining region elements. Proc.Natl.Acad.Sci.USA 85:8196-8200.
  • Marvel,J., J.Tassignon, M.Brait, K.Meek, E.C.B.Milner, M.Moser, J.D.Capra, and J.Urbain. 1987. Influence of Vk gene polymorphism on the induction of silent idiotypes in the arsonate system. Mol.Immunol. 24:463-470.
  • Milner,E.C.B. 1987. The immune system: Molecular genetic principles. Virginia Mason Cli.Bull. 40:155-162.
  • Jeske,D.J., E.C.B.Milner, O.Leo, M.Moser, J.Marvel, J.Urbain, and J.D.Capra. 1986. Molecular mapping of idiotopes of antiarsonate hybridomas. J.Immunol. 136:2568-2568.
  • Milner,E.C.B., K.D.Meek, G.Rathbun, P.Tucker, and J.D.Capra. 1986. Are anti-arsonate N-segments selected both at the protein and at the DNA level. Immunol.Today 7:36-40.
  • Urbain,J., G.Urbain-Vansanten, C.Demur, O.Leo, J.Marvel, M.Moser, J.Tassignon, M.Slaoui, K.Meek, E.C.B.Milner, and J.D.Capra. 1986. From Idiotypes to Idiotypic Networks. In Idiotypes. M.Reichlin and J.D.Capra, editors. Academic Press, Orlando. 111-138.
  • Leo,O., M.Slaoui, J.Marvel, E.C.B.Milner, J.Hiernaux, M.Moser, and J.D.Capra. 1985. Idiotypic analysis of polyclonal and monoclonal anti-arsonate antibodies of BALB/c mice expressing the major cross-reactive idiotype of the A/J strain. J.Immunol. 134:1734-1739.
  • Milner,E.C.B. and J.D.Capra. 1984. A serologic marker for the Ars-C family of anti-arsonate antibodies. Ann.Immunol.(Inst.Pasteur.) 135C:11-16.
  • Slaughter,C.A., D.J.Jeske, W.A.Kuziel, E.C.B.Milner, and J.D.Capra. 1984. Use of JH4 joining segment gene by an anti-arsonate antibody that bears the major A-strain cross-reactive idiotype but displays diminished antigen binding. J.Immunol. 132:3164-3171.
  • Milner,E.C.B. and J.D.Capra. 1983. Structural analysis of monoclonal anti-arsonate antibodies: Idiotypic specificities are determined by the heavy chain. Mol.Immunol. 20:39-46.
  • Milner,E.C.B., J.A.Rudbach, and K.B.von Eschen. 1983. Cellular responses to bacterial lipopolysaccharide: LPS facilitates priming of antigen-reactive T cells. Scand.J.Immunol. 18:29-35.
  • Milner,E.C.B., J.A.Rudbach, and K.B.von Eschen. 1983. Cellular responses to bacterial lipopolysaccharide: T cells recognize LPS determinants. Scand.J.Immunol. 18:21-28.
  • Capra,J.D., C.Slaughter, E.C.B.Milner, P.Estess, and P.W.Tucker. 1982. The cross-reactive idiotype of A-strain mice: serological and structural analysis. Immunol.Today 3:332-339.
  • Estess,P., F.Otani, E.C.B.Milner, J.D.Capra, and P.W.Tucker. 1982. Gene rearrangements in monoclonal A/J anti-arsonate antibodies. J.Immunol. 129:2319-2322.
  • Milner,E.C.B. and J.D.Capra. 1982. VH families in the antibody response to p-azophenylarsonate: correlation between serology and amino acid sequence. J.Immunol. 129:193-199.
  • Rudbach,J.A., F.I.Akiya, R.J.Elin, H.O.Hochstein, M.K.Luoma, E.C.B.Milner, K.C.Milner, and K.R.Thomas. 1976. Preparation and properties of a national reference endotoxin. J.Clin.Microbiol. 3:21-25.
    • ABSTRACTS
  • Chungwen Wei, Ramin Sabahi, Teresa Owen, Jennifer Barnard, Bo Zheng, Jennifer Anolik, Iñaki Sanz, and Eric C.B. Milner. A Unique Subset of SLE Patients with Naïve B Cell Expansion. Arthritis Rheum, 2006. (Astract)
  • Jennifer Anolik, Jonathan Friedberg, Jennifer Barnard, Teresa Owen, Bo Zheng, Chungwen Wei, Emily Cushing, Jennifer Kelly, Eric Milner, R John Looney, Richard Fisher, and Iñaki Sanz B cell reconstitution after rituximab recapitulates B cell ontogeny with a preponderance of transitional B cells and a paucity of memory B cells Arthritis Rheum, 2006. (Astract)
  • Bo Zheng, Teresa Owen, Chungwen Wei, Jennifer Barnard, Jennifer Anolik, Eric C. B. Milner, Ignacio Sanz. Characterization of a population of CD27-negative memory B cells expanded in SLE. Arthritis Rheum, 2006. (Astract)
  • C. Wei, J. Anolik, A. Cappione, J. Huggins, B. Zheng, E. C. B. Milner, and I. Sanz. Definition of a Novel Population of CD27-Negative Human Memory B-Cells and its Expansion in SLE. Arthritis Rheum, 2006. (Abstract)
  • J. H. Anolik, J. Barnard, A. J. Cappione, E. C. B. Milner, R. E. Felgar, R. J. Looney, and I. Sanz. B cell depletion with rituximab in human SLE. Keystone Symposium, 2005. (Abstract)
  • A. Cappione, J. Anolik, A. Pugh-Bernard, B. Zheng, C Wei, E. C. B. Milner, and I. Sanz. Definition of a novel population of CD27-negative human memory B-cells and its expansion in SLE. Keystone Symposia, 2005. (Abstract)
  • A. J. Cappione, J. Anolik, E. C. B. Milner, J. Barnard, A. Pugh-Bernard, P. Dutcher, and I. Sanz. Regulation of Autoreactive B-Cells. Keystone Symposia, 2005. (Abstract)
  • A. M. Glas, E. H. N. van Montfort, J. Storek, E. N. Green, and E. C. B. Milner. Somatic mutation deficit following bone marrow transplant. FASEB J. 14:A1044, 2000. (Abstract)
  • S.-C. Huang, G. V. Pinchuk, S. P. Rao, R. Jiang, E. H. N. van Montfort, A. M. Glas, and E. C. B. Milner. Somatic mutation in human B cells cultured in vitro . J.Allergy Clin.Immunol. 99:LB70, 1997. (Abstract)
  • E. C. B. Milner, S. P. Rao, P. Kraj, S.-C. Huang, G. V. Pinchuk, A. M. Glas, R. Jiang, R. R. Hardy, and L. E. Silberstein. The antibody repertoire in human B cell development: early, late, and persistent biases. J.Allergy Clin.Immunol. 99:459, 1997. (Abstract)
  • S. P. Rao, P. Kraj, A. M. Glas, R. R. Hardy, E. C. B. Milner, and L. E. Silberstein. The human VH family gene repertoire is biased at all stages of B cell ontogeny including early pre B cells. Keystone Symposia18, 1997. (Abstract)
  • G. V. Pinchuk, C. M. Alexander, R. J. Armitage, and E. C. B. Milner. VH4 repertoire of human B cells activated by CD40 ligand and IL-4. FASEB J. 10:A1165, 1996. (Abstract)
  • S.-C. Huang, W. O. Hufnagle, A. Glas, S. Rao, I. Suzuki, and E. C. B. Milner. Analysis of the VH repertoire in RA patients reveals an elevated antigen-driven component and a markedly diminished preimmune component . Arthritis Rheum 37:S287, 1994. (Abstract)
  • G. V. Pinchuk, C. Nottenburg, and E. C. B. Milner. Nonrandom association of V region gene segments in the human antibody response to Haemophilus influenzae capsular polysaccharide (Hib PS). FASEB J. 8:A983, 1994. (Abstract)
  • C. Nottenburg, L. Pfister, I. Suzuki-Jaecks, and E. C. B. Milner. Reconstitution of the B cell repertoire after bone marrow transplantation. J.Cell.Biochem. 17B:163, 1993. (Abstract)
  • I. Suzuki-Jaecks, A. M. Glas, L. Pfister, C. Nottenburg, and E. C. B. Milner. VH contribution to the human antibody repertoire. FASEB J.(supplement), 1993. (Abstract)
  • E. C. B. Milner, S. M. van der Maarel, K. Willems van Dijk, C. M. Alexander, and A. B. Bull. Chromosomal organization of a human VH gene family. Autoimmunity6, 1992. (Abstract)
  • E. C. B. Milner, S. M. van der Maarel, K. Willems van Dijk, C. M. Alexander, and A. B. Bull. Chromosomal organization of a human VH gene family. FASEB J. 6:A1223, 1992. (Abstract)
  • E. H. Sasso, K. Willems van Dijk, A. Bull, and E. C. B. Milner. A fetally expressed rheumatoid factor (RF) gene belongs to a complex set of VH alleles. Autoimmunity10, 1992. (Abstract)
  • K. Willems van Dijk, L. A. Milner, E. H. Sasso, and E. C. B. Milner. Chromosomal organization of the VH gene segments comprising the human fetal antibody repertoire. Autoimmunity7, 1992. (Abstract)
  • J. L. Hillson, E. H. Sasso, I. R. Oppliger, and E. C. B. Milner. Variation in the newly-emerging B cell repertoire associated with polymorphism at the VH locus. Arthritis Rheum 34 (Supplement):S35, 1991. (Abstract)
  • E. C. B. Milner, K. Willems van Dijk, L. A. Milner, and E. H. Sasso. Chromosomal organization of developmentally expressed human VH genes. Arth.Fdn.Fel.Conf.62, 1991. (Abstract)
  • E. H. Sasso, K. Willems van Dijk, and E. C. B. Milner. Polymorphism and prevalence of human VH germline genes. Arthritis Rheum, 1991. (Abstract)
  • E. H. Sasso, K. Willems van Dijk, A. Bull, and E. C. B. Milner. Prevalence and polymorphism of human VH germline genes. FASEB J. 5:A1774, 1991. (Abstract)
  • K. Willems van Dijk, L. A. Milner, E. H. Sasso, and E. C. B. Milner. Chromosomal organization of developmentally expressed human VH genes. J.Cell.Biochem. 15A:266, 1991. (Abstract)
  • K. Willems van Dijk, L. A. Milner, E. H. Sasso, and E. C. B. Milner. Chromosomal organization of developmentally expressed human VH genes. FASEB J. 5:A1774, 1991. (Abstract)
  • E. C. B. Milner, K. Willems van Dijk, and E. H. Sasso. Polymorphism of human immunoglobulin VH genes. FASEB J.(supplement), 1990. (Abstract)
  • E. C. B. Milner, K. D. Meek, and J. D. Capra. Anti-arsonate antibody N-segments apear to be under selection both at the protein and at the DNA level. Arth.Fdn.Fel.Conf., 1985. (Abstract)
  • P. Estess, E. C. B. Milner, C. Slaughter, P. Tucker, and J. D. Capra. A genetic mechanism for the differential expression of an immunoglobulin VH marker. J.Cell.Biochem., 1982. (Abstract)
  • E. C. B. Milner, J. A. Rudbach, and K. B. von Eschen. T cell responses to bacterial lipopolysaccharide. Am.Soc.Micro., 1980. (Abstract)